PTPN9 antibody (C-Term)

Catalog No. ABIN2793387

Product Details anti-PTPN9 Antibody

Target: PTPN9 (Protein tyrosine Phosphatase, Non-Receptor Type 9 (PTPN9))

Binding Specificity: AA 477-505, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPN9 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purpose: Rabbit Anti-Human MEG2 (C-term) Antibody

Immunogen: This MEG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 477-505 amino acids from the C-terminal region of human MEG2.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50The anti-MEG2 Pab , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2.0 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for PTPN9

Target: PTPN9 (Protein tyrosine Phosphatase, Non-Receptor Type 9 (PTPN9))

Alternative Name: MEG2 (PTPN9 Products)

Synonyms: MEG2 antibody, PTPMEG2 antibody, Meg2 antibody, protein tyrosine phosphatase, non-receptor type 9 antibody, ptpn9 antibody, PTPN9 antibody, Ptpn9 antibody

Background:

Target Description: MEG2 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain that shares a significant similarity with yeast SEC14, which is a protein that has phosphatidylinositol transfer activity and is required for protein secretion through the Golgi complex in yeast. This PTP was found to be activated by polyphosphoinositide, and is thought to be involved in signaling events regulating phagocytosis.

Gene Symbol: PTPN9

Molecular Weight: 68020 Da

Gene ID: 5780

UniProt: P43378