PAAF1 antibody (N-Term)

Catalog No. ABIN2794640

Product Details anti-PAAF1 Antibody

Target: PAAF1 (Proteasomal ATPase-Associated Factor 1 (PAAF1))

Binding Specificity: AA 109-138, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAAF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purpose: Rabbit Anti-Human PAAF1 (N-term) Antibody

Immunogen: This PAAF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-138 amino acids from the N-terminal region of human PAAF1.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:50-100Western blot analysis of PAAF1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for PAAF1

Target: PAAF1 (Proteasomal ATPase-Associated Factor 1 (PAAF1))

Alternative Name: PAAF1 (PAAF1 Products)

Synonyms: paaf antibody, rpn14 antibody, wdr71 antibody, WDR71 antibody, MGC146521 antibody, PAAF antibody, Rpn14 antibody, proteasomal ATPase associated factor 1 S homeolog antibody, proteasomal ATPase associated factor 1 antibody, paaf1.S antibody, PAAF1 antibody, paaf1 antibody, Paaf1 antibody

Background:

Target Description: PAAF1 inhibits proteasome 26S assembly and proteolytic activity by impairing the association of the 19S regulatory complex with the 20S core. In case of HIV-1 infection, recruited by viral Tat to the HIV-1 promoter, where it promotes the recruitment of 19S regulatory complex through dissociation of the proteasome 26S. This presumably promotes provirus transcription efficiency.

Gene Symbol: PAAF1

Molecular Weight: 42190 Da

Gene ID: 80227

UniProt: Q9BRP4