PCDHGA5 antibody (N-Term)

Catalog No. ABIN2795315

Product Details anti-PCDHGA5 Antibody

Target: PCDHGA5 (Protocadherin gamma Subfamily A, 5 (PCDHGA5))

Binding Specificity: AA 254-280, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDHGA5 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit Anti-Human PCDHGA5 (N-term) Antibody

Immunogen: This PCDHGA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 254-280 amino acids from the N-terminal region of human PCDHGA5.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot
Recommended Dilutions
WB: 1:1000PCDHGA5 Antibody (N-term) .

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for PCDHGA5

Target: PCDHGA5 (Protocadherin gamma Subfamily A, 5 (PCDHGA5))

Alternative Name: PCDHGA5 (PCDHGA5 Products)

Synonyms: CDH-GAMMA-A5 antibody, ME3 antibody, PCDH-GAMMA-A5 antibody, protocadherin gamma subfamily A, 5 antibody, protocadherin gamma-A5 antibody, PCDHGA5 antibody, Pcdhga5 antibody, LOC100516665 antibody

Background:

Target Description: This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

Gene Symbol: PCDHGA5

Molecular Weight: 100935 Da

Gene ID: 56110

UniProt: Q9Y5G8