PCDHGB4 antibody (Center)
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- Target See all PCDHGB4 Antibodies
- PCDHGB4 (Protocadherin gamma Subfamily B, 4 (PCDHGB4))
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Binding Specificity
- AA 353-379, Center
- Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PCDHGB4 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purpose
- Rabbit Anti-Human PCDHGB4 (Center) Antibody
- Immunogen
- This PCDHGB4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 353-379 amino acids from the Central region of human PCDHGB4.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product PCDHGB4 Primary Antibody
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- Application Notes
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Western Blot
Recommended Dilutions
WB: 1:1000PCDHGB4 Antibody (Center). - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.300 mg/mL
- Storage
- 4 °C,-20 °C
- Storage Comment
- 2-8°C (short-term), -20°C (long-term)
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- Target
- PCDHGB4 (Protocadherin gamma Subfamily B, 4 (PCDHGB4))
- Alternative Name
- PCDHGB4 (PCDHGB4 Products)
- Synonyms
- CDH20 antibody, FIB2 antibody, PCDH-GAMMA-B4 antibody, protocadherin gamma subfamily B, 4 antibody, PCDHGB4 antibody, Pcdhgb4 antibody
- Background
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Target Description: This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. This particular family member is expressed in fibroblasts and is thought to play a role in wound healing in response to injury. Alternative splicing has been described for the gamma cluster genes.
Gene Symbol: PCDHGB4
- Molecular Weight
- 99927 Da
- Gene ID
- 8641
- UniProt
- Q9UN71
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