EXOSC6 antibody (N-Term)

Catalog No. ABIN2795600

Product Details anti-EXOSC6 Antibody

Target: EXOSC6 (Exosome Component 6 (EXOSC6))

Binding Specificity: AA 12-38, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EXOSC6 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit Anti-Human EXOSC6 (N-term) Antibody

Immunogen: This EXOSC6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-38 amino acids from the N-terminal region of human EXOSC6.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot
Recommended Dilutions
WB: 1:1000EXOSC6 Antibody (N-term) .

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for EXOSC6

Target: EXOSC6 (Exosome Component 6 (EXOSC6))

Alternative Name: EXOSC6 (EXOSC6 Products)

Synonyms: exosc6 antibody, RAR-gamma antibody, id:ibd1130 antibody, wu:fe17d05 antibody, zgc:110071 antibody, EAP4 antibody, MTR3 antibody, Mtr3p antibody, hMtr3p antibody, p11 antibody, 2610510N21Rik antibody, C76919 antibody, Mtr3 antibody, exosome component 6 antibody, EXOSC6 antibody, exosc6 antibody, CpipJ_CPIJ018071 antibody, Exosc6 antibody

Background:

Target Description: This gene product constitutes one of the subunits of the multisubunit particle called exosome, which mediates mRNA degradation. The composition of human exosome is similar to its yeast counterpart. This protein is homologous to the yeast Mtr3 protein. Its exact function is not known, however, it has been shown using a cell-free RNA decay system that the exosome is required for rapid degradation of unstable mRNAs containing AU-rich elements (AREs), but not for poly(A) shortening. The exosome does not recognize ARE-containing mRNAs on its own, but requires ARE-binding proteins that could interact with the exosome and recruit it to unstable mRNAs, thereby promoting their rapid degradation.

Gene Symbol: EXOSC6

Molecular Weight: 28235 Da

Gene ID: 118460

UniProt: Q5RKV6

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response