SIKE1 antibody (N-Term)

Catalog No. ABIN2796031

Product Details anti-SIKE1 Antibody

Target: SIKE1 (Suppressor of IKBKE 1 (SIKE1))

Binding Specificity: AA 36-63, N-Term

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIKE1 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit Anti-Mouse Mouse Sike1 (N-term) Antibody

Immunogen: This Mouse Sike1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-63 amino acids from the N-terminal region of mouse Sike1.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot
Recommended Dilutions
WB: 1:1000MOUSE Sike1 Antibody (N-term) .

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.380 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for SIKE1

Target: SIKE1 (Suppressor of IKBKE 1 (SIKE1))

Alternative Name: Sike1 (SIKE1 Products)

Synonyms: SIKE antibody, 2810005O12Rik antibody, 5730470L24Rik antibody, AI450236 antibody, AI839862 antibody, Sike antibody, Sikeb antibody, RGD1311316 antibody, suppressor of IKBKE 1 antibody, SIKE1 antibody, Sike1 antibody

Background:

Target Description: Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus-and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways (By similarity).

Gene Symbol: Sike1

Molecular Weight: 23522 Da

Gene ID: 66641

UniProt: Q9CPR7