TMEM43 antibody (Center)

Catalog No. ABIN2797836

Product Details anti-TMEM43 Antibody

Target: TMEM43 (Transmembrane Protein 43 (TMEM43))

Binding Specificity: AA 195-223, Center

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM43 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Purpose: Rabbit Anti-Human TMEM43 (Center) Antibody

Immunogen: This TMEM43 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-223 amino acids from the Central region of human TMEM43.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50TMEM43 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for TMEM43

Target: TMEM43 (Transmembrane Protein 43 (TMEM43))

Alternative Name: TMEM43 (TMEM43 Products)

Synonyms: zgc:85946 antibody, ARVC5 antibody, ARVD5 antibody, EDMD7 antibody, LUMA antibody, 1200015A22Rik antibody, transmembrane protein 43 antibody, TMEM43 antibody, tmem43 antibody, Tmem43 antibody

Background:

Target Description: This gene belongs to the TMEM43 family. Defects in this gene are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5), also known as arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5). Arrhythmogenic right ventricular dysplasia is an inherited disorder, often involving both ventricles, and is characterized by ventricular tachycardia, heart failure, sudden cardiac death, and fibrofatty replacement of cardiomyocytes. This gene contains a response element for PPAR gamma (an adipogenic transcription factor), which may explain the fibrofatty replacement of the myocardium, a characteristic pathological finding in ARVC.

Gene Symbol: TMEM43

Molecular Weight: 44876 Da

Gene ID: 79188

UniProt: Q9BTV4