FAM33A antibody (N-Term)
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- Target See all FAM33A Antibodies
- FAM33A (Spindle and Kinetochore-Associated Protein 2 (FAM33A))
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Binding Specificity
- AA 9-37, N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FAM33A antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Purpose
- Rabbit Anti-Human SKA2 (N-term) Antibody
- Immunogen
- This SKA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-37 amino acids from the N-terminal region of human SKA2.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product FAM33A Primary Antibody
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- Application Notes
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Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50SKA2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Storage
- 4 °C,-20 °C
- Storage Comment
- 2-8°C (short-term), -20°C (long-term)
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- Target
- FAM33A (Spindle and Kinetochore-Associated Protein 2 (FAM33A))
- Alternative Name
- SKA2 (FAM33A Products)
- Synonyms
- FAM33A antibody, 1110001A07Rik antibody, C78640 antibody, Fam33a antibody, RGD1307084 antibody, fam33a antibody, spindle and kinetochore associated complex subunit 2 antibody, Spindle and kinetochore-associated protein 2 antibody, SKA2 antibody, Ska2 antibody, ska2 antibody
- Background
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Target Description: Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it is required for SKA1 localization.
Gene Symbol: SKA2
- Molecular Weight
- 14188 Da
- Gene ID
- 348235
- UniProt
- Q8WVK7
- Pathways
- M Phase
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