PTPN18 antibody (C-Term)
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- Target See all PTPN18 Antibodies
- PTPN18 (Protein tyrosine Phosphatase, Non-Receptor Type 18 (Brain-Derived) (PTPN18))
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Binding Specificity
- AA 430-459, C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PTPN18 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purpose
- Rabbit Anti-Human PTPN18 (C-term) Antibody
- Immunogen
- This PTPN18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 430-459 amino acids from the C-terminal region of human PTPN18.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product PTPN18 Primary Antibody
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- Application Notes
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Western Blot
Recommended Dilutions
WB: 1:1000PTPN18 Antibody (C-term) with the PTPN18 gene. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Storage
- 4 °C,-20 °C
- Storage Comment
- 2-8°C (short-term), -20°C (long-term)
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- Target
- PTPN18 (Protein tyrosine Phosphatase, Non-Receptor Type 18 (Brain-Derived) (PTPN18))
- Alternative Name
- PTPN18 (PTPN18 Products)
- Synonyms
- BDP1 antibody, PTP-HSCF antibody, FLP1 antibody, HSCF antibody, PTP-K1 antibody, Ptpk1 antibody, PTP20 antibody, protein tyrosine phosphatase, non-receptor type 18 antibody, PTPN18 antibody, Ptpn18 antibody
- Background
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Target Description: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, the mitotic cycle, and oncogenic transformation. This PTP contains a PEST motif, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-live. This protein can differentially dephosphorylate autophosphorylated tyrosine kinases that are overexpressed in tumor tissues, and it appears to regulate HER2, a member of the epidermal growth factor receptor family of receptor tyrosine kinases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Gene Symbol: PTPN18
- Molecular Weight
- 50482 Da
- Gene ID
- 26469
- UniProt
- Q99952
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