MTIF2 antibody (N-Term)

Catalog No. ABIN2799247

Product Details anti-MTIF2 Antibody

Target: MTIF2 (Mitochondrial Translational Initiation Factor 2 (MTIF2))

Binding Specificity: AA 138-167, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTIF2 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit Anti-Human MTIF2 (N-term) Antibody

Immunogen: This MTIF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-167 amino acids from the N-terminal region of human MTIF2.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot
Recommended Dilutions
WB: 1:1000Western blot analysis of lysate from SK-BR-3 cell line, using MTIF2 Antibody (N-term) at 1:5000 dilution was used as the secondary antibody. Lysate at 35 μg per lane.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for MTIF2

Target: MTIF2 (Mitochondrial Translational Initiation Factor 2 (MTIF2))

Alternative Name: MTIF2 (MTIF2 Products)

Synonyms: fb59c03 antibody, wu:fb59c03 antibody, zgc:162191 antibody, DKFZp469E0732 antibody, 2310038D14Rik antibody, 2410112O06Rik antibody, IF-2(Mt) antibody, IF-2mt antibody, IF2(mt) antibody, mitochondrial translational initiation factor 2 antibody, MTIF2 antibody, mtif2 antibody, Mtif2 antibody

Background:

Target Description: During the initiation of protein biosynthesis, initiation factor-2 (IF-2) promotes the binding of the initiator tRNA to the small subunit of the ribosome in a GTP-dependent manner. Prokaryotic IF-2 is a single polypeptide, while eukaryotic cytoplasmic IF-2 (eIF-2) is a trimeric protein. Bovine liver mitochondria contain IF-2(mt), an 85-kD monomeric protein that is equivalent to prokaryotic IF-2. The predicted 727-amino acid human protein contains a 29-amino acid presequence. Human IF-2(mt) shares 32 to 38 % amino acid sequence identity with yeast IF-2(mt) and several prokaryotic IF-2s, with the greatest degree of conservation in the G domains of the proteins. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].

Gene Symbol: MTIF2

Molecular Weight: 81317 Da

Gene ID: 4528

UniProt: P46199

Pathways: Ribonucleoprotein Complex Subunit Organization