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PAR1 antibody

F2R Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1944818
  • Target See all PAR1 (F2R) Antibodies
    PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))
    Reactivity
    • 68
    • 25
    • 23
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Host
    • 61
    • 7
    • 2
    Rabbit
    Clonality
    • 64
    • 6
    Polyclonal
    Conjugate
    • 39
    • 7
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PAR1 antibody is un-conjugated
    Application
    • 60
    • 36
    • 13
    • 13
    • 11
    • 8
    • 8
    • 6
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Isotype
    IgG1
    Top Product
    Discover our top product F2R Primary Antibody
  • Application Notes
    WB: 1:500- 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    Storage
    4 °C,-20 °C
  • Zania, Gourni, Aplin, Nicosia, Flordellis, Maragoudakis, Tsopanoglou: "Parstatin, the cleaved peptide on proteinase-activated receptor 1 activation, is a potent inhibitor of angiogenesis." in: The Journal of pharmacology and experimental therapeutics, Vol. 328, Issue 2, pp. 378-89, (2009) (PubMed).

    Kahn, Nakanishi-Matsui, Shapiro, Ishihara, Coughlin: "Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin." in: The Journal of clinical investigation, Vol. 103, Issue 6, pp. 879-87, (1999) (PubMed).

    Shapiro, Trejo, Zeng, Coughlin: "Role of the thrombin receptor's cytoplasmic tail in intracellular trafficking. Distinct determinants for agonist-triggered versus tonic internalization and intracellular localization." in: The Journal of biological chemistry, Vol. 271, Issue 51, pp. 32874-80, (1997) (PubMed).

  • Target
    PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))
    Alternative Name
    Thrombin Receptor (F2R Products)
    Synonyms
    CF2R antibody, HTR antibody, PAR-1 antibody, PAR1 antibody, TR antibody, Par1 antibody, TRGPC antibody, AI482343 antibody, Cf2r antibody, ThrR antibody, Par-1 antibody, f2r-a antibody, par1 antibody, coagulation factor II thrombin receptor antibody, coagulation factor II (thrombin) receptor antibody, coagulation factor 2 (thrombin) receptor L homeolog antibody, F2R antibody, F2r antibody, f2r.L antibody
    Background
    High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.
    Molecular Weight
    47441 Da
    Gene ID
    2149
    UniProt
    P25116
    Pathways
    Nuclear Receptor Transcription Pathway, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus
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