LRRC6 antibody (AA 201-300) (Alexa Fluor 594)

Catalog No. ABIN2803861

Product Details anti-LRRC6 Antibody (Alexa Fluor 594)

Target: LRRC6 (Leucine Rich Repeat Containing 6 (LRRC6))

Binding Specificity: AA 201-300

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRRC6 antibody is conjugated to Alexa Fluor 594

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LRRC6

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for LRRC6

Target: LRRC6 (Leucine Rich Repeat Containing 6 (LRRC6))

Alternative Name: LRRC6 (LRRC6 Products)

Synonyms: LRTP antibody, Lrtp antibody, Tslrp antibody, CILD19 antibody, TSLRP antibody, lrrc6l antibody, leucine rich repeat containing 6 (testis) antibody, leucine rich repeat containing 6 antibody, Lrrc6 antibody, LRRC6 antibody, lrrc6 antibody

Background:

Synonyms: Leucine rich repeat containing 6, Leucine rich repeat containing protein 6, Leucine rich testis specic protein, Leucine-rich repeat-containing protein 6, Leucine-rich testis-specic protein, Lrrc6, LRTP, Protein TILB homolog, Testis specic leucine rich repeat protein, Testis-specic leucine-rich repeat protein, TILB_HUMAN, TSLRP.

Background: The leucine-rich repeat-containing protein 6 (LRRC6), also designated Leucine-rich testis-specific protein (LRTP), is a 466 amino acid protein that contains 3 LRR repeats and plays a role in spermatogenesis. The gene encoding LRRC6 maps to chromosome 8, which encodes approximately 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and typically associated with a poor prognosis. Chromosome 8 is also associated with Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome.

Pathways: M Phase