SH3GL3 antibody (AA 121-220) (Alexa Fluor 594)

Catalog No. ABIN2806336

Product Details anti-SH3GL3 Antibody (Alexa Fluor 594)

Target: SH3GL3 (Endophilin-A3 (SH3GL3))

Binding Specificity: AA 121-220

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SH3GL3 antibody is conjugated to Alexa Fluor 594

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Cow,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SH3GL3

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for SH3GL3

Target: SH3GL3 (Endophilin-A3 (SH3GL3))

Alternative Name: SH3GL3 (SH3GL3 Products)

Synonyms: EEN-B2 antibody, SH3P13 antibody, Sh3d2c antibody, Sh3d2c2 antibody, CNSA3 antibody, EEN-2B-L3 antibody, HsT19371 antibody, SH3D2C antibody, Sh3d2c1 antibody, SH3-domain GRB2-like 3 antibody, SH3 domain containing GRB2 like 3, endophilin A3 antibody, Sh3gl3 antibody, SH3GL3 antibody

Background:

Synonyms: Endophilin I-III, Endophilin-III, CNSA3, EEN 2B L3, EEN B2, EEN2BL3, EENB2, Endophilin 3, Endophilin A3, H.sapiens mRNA for protein containing SH3 domain, SH3GL3, HsT19371, SH3 domain containing GRB2 like protein 3, SH3 domain GRB2 like 3, SH3 domain protein 2C, SH3D2C, SH3P13, SH3G3_HUMAN.

Background: The endophilins comprise a family of three SH3 domain-containing proteins designated Endophilin I, II and III, or alternatively known as SH3P4, SH3P8 and SH3P13, respectively. These proteins associate with Amphiphysin, Synaptojanin and Dynamin and are implicated in presynaptic vesicle trafficking at nerve terminals. The expression patterns of the endophilins are consistent with their cellular functions at the neuronal synapse, as Endophilin I is ex- pressed only in the brain. Both Endophilin II and Endophilin III are detected in a variety of tissues. Endophilin I is also implicated in modulating G protein-coupled receptor signaling by functioning as an adapter protein and directing 1 adrenergic receptors to the endocytic machinery.