Angiotensin 1 (AA 34-43) antibody (Alexa Fluor 594)

Catalog No. ABIN2809730

Product Details

Target: Angiotensin 1

Binding Specificity: AA 34-43

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Alexa Fluor 594

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Specificity: Immunogen used for this antibody is DRVYIHPFHL, corresponding to amino acids 34-43 of human Angiotensinogen.

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Sheep,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide of human Angiotensin I

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: Angiotensin 1

Background:

Synonyms: AGT, Alpha 1 antiproteinase antitrypsin, Ang I, Ang II, Ang III, Angiotensin 1, Angiotensin, Angiotensin I, Angiotensin II, Angiotensin-2, Angiotensin III, Angiotensin-3, Angiotensinogen, Angiotensinogen serpin peptidase inhibitor clade A member 8, ANGT_HUMAN, Angiotensin 1-10, Angiotensin 1-8, ANHU, Des-Asp[1]-angiotensin II, FLJ92595, FLJ97926, OTTHUMP00000035878, Pre angiotensinogen, Serine or cysteine proteinase inhibitor, Serpin A8, Serpin peptidase inhibitor, clade A, member 8, SERPINA8.

Background: Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. Angiotensin-2: acts directly on vascular smooth muscle as a potent vasoconstrictor, affects cardiac contractility and heart rate through its action on the sympathetic nervous system, and alters renal sodium and water absorption through its ability to stimulate the zona glomerulosa cells of the adrenal cortex to synthesize and secrete aldosterone. Angiotensin-3: stimulates aldosterone release. Angiotensin 1-7: is a ligand for the G-protein coupled receptor MAS1. Has vasodilator and antidiuretic effects. Has an antithrombotic effect that involves MAS1-mediated release of nitric oxide from platelets.

Gene ID: 183