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CCDC40 antibody (AA 851-950) (Alexa Fluor 594)

CCDC40 Reactivity: Human IF (cc), IF (p) Host: Rabbit Polyclonal Alexa Fluor 594
Catalog No. ABIN2811219
  • Target See all CCDC40 Antibodies
    CCDC40 (Coiled-Coil Domain Containing 40 (CCDC40))
    Binding Specificity
    • 14
    • 1
    AA 851-950
    Reactivity
    Human
    Host
    • 15
    • 1
    Rabbit
    Clonality
    • 16
    Polyclonal
    Conjugate
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CCDC40 antibody is conjugated to Alexa Fluor 594
    Application
    • 12
    • 12
    • 4
    • 3
    • 3
    • 2
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CCDC4
    Isotype
    IgG
    Top Product
    Discover our top product CCDC40 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    CCDC40 (Coiled-Coil Domain Containing 40 (CCDC40))
    Alternative Name
    CCDC40 (CCDC40 Products)
    Synonyms
    CILD15 antibody, B930008I02Rik antibody, im:7149866 antibody, lok antibody, si:dkey-237i9.5 antibody, wu:fb11d02 antibody, coiled-coil domain containing 40 antibody, CCDC40 antibody, Ccdc40 antibody, ccdc40 antibody
    Background

    Synonyms: CCD40_HUMAN, ccdc 40, CCDC40, Coiled coil domain containing 40, coiled-coil domain containing 40, Coiled-coil domain-containing protein 40.

    Background: Required for assembly of dynein regulatory complex (DRC) and inner dynein arm complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Not required for outer dynein arm complexes assembly. Required for axonemal recruitment of CCDC39.Involvement in disease:Defects in CCDC40 are the cause of primary ciliary dyskinesia type 15 (CILD15) . A disorder characterized by abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia, reduced fertility is often observed in male patients due to abnormalities of sperm tails. Half of the patients exhibit randomization of left-right body asymmetry and situs inversus, due to dysfunction of monocilia at the embryonic node. Primary ciliary dyskinesia associated with situs inversus is referred to as Kartagener syndrome.

    Gene ID
    55036
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