CXX1 antibody (Alexa Fluor 594)

Catalog No. ABIN2811578

Product Details anti-CXX1 Antibody (Alexa Fluor 594)

Target: CXX1 (FAM127A) (Family with Sequence Similarity 127, Member A (FAM127A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXX1 antibody is conjugated to Alexa Fluor 594

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CXX1/Cerebral protein 5

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CXX1

Target: CXX1 (FAM127A) (Family with Sequence Similarity 127, Member A (FAM127A))

Alternative Name: Cerebral protein 5 (FAM127A Products)

Synonyms: CXX1 antibody, MAR8C antibody, MART8C antibody, Mar8 antibody, Mart8 antibody, retrotransposon Gag like 8C antibody, RTL8C antibody

Background:

Synonyms: Mammalian retrotransposon derived protein 8C, CAAX box protein 1, Cerebral protein 5, CXX 1, FAM127A, Family with sequence similarity 127, member A, Mar8, MAR8C, Mart8, F127A_HUMAN.

Background: The X and Y chromosomes are the human sex chromosomes. Chromosome X consists of about 153 million base pairs and nearly 1,000 genes. The combination of an X and Y chromosome lead to normal male development while two copies of X lead to normal female development. There are a number of conditions related to an unsual number and combination of sex chromosomes being inherited. More than one copy of the X chromosome with a Y chromosome causes Klinefelter's syndrome. A single copy of X alone leads to Turner's syndrome. More than 2 copies of the X chromosome, in the absence of a Y chromosome, is known as Triple X syndrome. Color blindness, hemophilia, and Duchenne muscular dystrophy are well known X chromosome-linked conditions which affect males more frequently as males carry a single X chromosome. The CXX1 gene product has been provisionally designated CXX1 pending further characterization.

Gene ID: 8933