CSGALNACT1 antibody (AA 101-200) (Alexa Fluor 594)

Catalog No. ABIN2811985

Product Details anti-CSGALNACT1 Antibody (Alexa Fluor 594)

Target: CSGALNACT1 (Chondroitin Sulfate N-Acetylgalactosaminyltransferase 1 (CSGALNACT1))

Binding Specificity: AA 101-200

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CSGALNACT1 antibody is conjugated to Alexa Fluor 594

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CSGALNACT1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CSGALNACT1

Target: CSGALNACT1 (Chondroitin Sulfate N-Acetylgalactosaminyltransferase 1 (CSGALNACT1))

Alternative Name: CSGALNACT1 (CSGALNACT1 Products)

Synonyms: CSGalNAcT-1 antibody, ChGn antibody, beta4GalNAcT antibody, CHGN antibody, 4732435N03Rik antibody, Chgn antibody, RGD1307618 antibody, chondroitin sulfate N-acetylgalactosaminyltransferase 1 antibody, CSGALNACT1 antibody, csgalnact1 antibody, Csgalnact1 antibody, LOC100517735 antibody

Background:

Synonyms: 4-N-acetylgalactosaminyltransferase 1, Beta4GalNAcT 1, beta4GalNAcT, Beta4GalNAcT-1, Beta4GalNAcT1, CGAT1_HUMAN, ChGn, Chondroitin beta-1, Chondroitin beta1 4 N acetylgalactosaminyltransferase, Chondroitin beta1 4 N acetylgalactosaminyltransferase 1, Chondroitin sulfate N acetylgalactosaminyltransferase 1, Chondroitin sulfate N-acetylgalactosaminyltransferase 1, CSGalNAcT 1, CsGalNAcT-1, Csgalnact1, FLJ11264, FLJ13760.

Background: The chondroitin N-acetylgalactosaminyltransferase family includes Beta-1,4-GalNAc-T, Beta-1,4-GalNAc-T2, Beta-1,4-GalNAc-T3 and Beta-1,4-GalNAc-T4. The Beta-1,4-GalNAc-T protein consists of a short N-terminal residue, a transmembrane region and a long C-terminal residue, which includes a catalytic domain and localizes to the Golgi apparatus. Beta-1,4-GalNAc-T utilizes simple ganglioside GM3 as a substrate for more complex gangliosides GM2, GM1 and GD1a. Beta-1,4-GalNAc-T is expressed in normal brain tissues and in various malignant transformed cells, such as malignant melanoma, neuroblastoma and adult T cell leukemia. Mice lacking the Beta-1,4-GalNAc-T protein develop significant and progressive behavioral neuropathies, including deficits in reflexes, strength, coordination and balance. Beta-1,4-GalNAc-T is a potential molecular marker for detecting melanoma cells and monitoring tumor progression.

Gene ID: 55790

Pathways: Glycosaminoglycan Metabolic Process