FAM36A antibody (AA 51-118) (Alexa Fluor 594)

Catalog No. ABIN2813081

Product Details anti-FAM36A Antibody (Alexa Fluor 594)

Target: FAM36A (Family with Sequence Similarity 36, Member A (FAM36A))

Binding Specificity: AA 51-118

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAM36A antibody is conjugated to Alexa Fluor 594

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FAM36A

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for FAM36A

Target: FAM36A (Family with Sequence Similarity 36, Member A (FAM36A))

Alternative Name: FAM36A (FAM36A Products)

Synonyms: FAM36A antibody, 2310005N03Rik antibody, Fam36a antibody, RGD1309105 antibody, cox20 antibody, fam36a antibody, COX20, cytochrome c oxidase assembly factor antibody, COX20 Cox2 chaperone antibody, COX20 cytochrome C oxidase assembly factor antibody, COX20 cytochrome c oxidase assembly factor L homeolog antibody, COX20 antibody, Cox20 antibody, cox20.L antibody

Background:

Synonyms: FAM 36A, Family with sequence similarity 36 member A, FLJ43269, Hypothetical protein LOC116228, OTTHUMP00000038200, Protein FAM36A.

Background: FAM36A is a multi-pass membrane protein. It belongs to the FAM36 family. The exact function of FAM36A remains unknown.Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The FAM36A gene product has been provisionally designated FAM36A pending further characterization.

Gene ID: 116228