GNA13 antibody (AA 21-120) (Alexa Fluor 594)

Catalog No. ABIN2813452

Product Details anti-GNA13 Antibody (Alexa Fluor 594)

Target: GNA13 (Guanine Nucleotide Binding Protein (G Protein), alpha 13 (GNA13))

Binding Specificity: AA 21-120

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNA13 antibody is conjugated to Alexa Fluor 594

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat,Cow,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human G protein alpha 13

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GNA13

Target: GNA13 (Guanine Nucleotide Binding Protein (G Protein), alpha 13 (GNA13))

Alternative Name: G protein alpha 13 (GNA13 Products)

Synonyms: Galpha13 antibody, gna13 antibody, wu:fe25e05 antibody, zgc:112436 antibody, Gna13 antibody, fj64c01 antibody, wu:fj64c01 antibody, GNA13 antibody, G13 antibody, AU024132 antibody, AU043124 antibody, G protein subunit alpha 13 antibody, guanine nucleotide binding protein (G protein), alpha 13a antibody, guanine nucleotide binding protein (G protein), alpha 13b antibody, guanine nucleotide binding protein, alpha 13 antibody, Gna13 antibody, gna13a antibody, gna13b antibody, GNA13 antibody

Background:

Synonyms: G alpha 13, GNA13, Guanine nucleotide binding protein alpha 13 subunit, GNA13_HUMAN.

Background: Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors. Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (i.e., adenyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein Alpha, Beta and Gamma polypeptides are encoded by at least 16, 4 and 7 genes, respectively. Most interest in G proteins has been focused on their Alpha subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Four distinct classes of G Alpha subunits have been identified, these include G Alpha s, G Alpha i, G Alpha q and G Alpha 12/13. The two members of the fourth class of G Alpha subunit proteins, G Alpha 12 and G Alpha 13, are insensitive to ADP-ribosylation by pertussis toxin, share 67 % identity with each other and less than 45 % identity with other G Alpha subunits and are widely expressed in a broad range of tissues.

Gene ID: 10672

Pathways: CXCR4-mediated Signaling Events