STAM antibody

Catalog No. ABIN2828328

Product Details anti-STAM Antibody

Target: STAM (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STAM antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Purification: Affinity purification

Immunogen: Recombinant protein of human STAM

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for STAM

Target: STAM (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM))

Alternative Name: STAM (STAM Products)

Synonyms: STAM-1 antibody, STAM1 antibody, wu:fv75b10 antibody, zgc:55725 antibody, RGD1564499 antibody, signal transducing adaptor molecule antibody, signal transducing adapter molecule 1 antibody, Signal transducing adapter molecule 1 antibody, signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 antibody, STAM antibody, CpipJ_CPIJ003516 antibody, Tsp_03939 antibody, stam-1 antibody, Stam antibody, stam antibody

Background: This gene encodes a member of the signal-transducing adaptor molecule family. These proteins mediate downstream signaling of cytokine receptors and also play a role in ER to Golgi trafficking by interacting with the coat protein II complex. The encoded protein also associates with hepatocyte growth factor-regulated substrate to form the endosomal sorting complex required for transport-0 (ESCRT-0), which sorts ubiquitinated membrane proteins to the ESCRT-1 complex for lysosomal degradation. Alternatively spliced transcript variants have been observed for this gene.

Pathways: EGFR Signaling Pathway, EGFR Downregulation