HIST1H2AG antibody (AA 63-87)

Catalog No. ABIN2838556

Product Details anti-HIST1H2AG Antibody

Target: HIST1H2AG (Histone Cluster 1, H2ag (HIST1H2AG))

Binding Specificity: AA 63-87

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HIST1H2AG antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: Rat, B, X, Y, C, Pr, Zf, D

Immunogen: This HIST1H2AG antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 63-87 amino acids from the Central region of human HIST1H2AG.

Clone: RB48738

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-HIST1H2AG antibody (ABIN2838556)

Marzluff, Gongidi, Woods, Jin, Maltais: "The human and mouse replication-dependent histone genes." in: Genomics, Vol. 80, Issue 5, pp. 487-98, (2002) (PubMed).

Albig, Trappe, Kardalinou, Eick, Doenecke: "The human H2A and H2B histone gene complement." in: Biological chemistry, Vol. 380, Issue 1, pp. 7-18, (1999) (PubMed).

Albig, Doenecke: "The human histone gene cluster at the D6S105 locus." in: Human genetics, Vol. 101, Issue 3, pp. 284-94, (1998) (PubMed).

Mannironi, Orr, Hatch, Pilch, Ivanova, Bonner: "The relative expression of human histone H2A genes is similar in different types of proliferating cells." in: DNA and cell biology, Vol. 13, Issue 2, pp. 161-70, (1994) (PubMed).

Dobner, Wolf, Mai, Lipp: "A novel divergently transcribed human histone H2A/H2B gene pair." in: DNA sequence : the journal of DNA sequencing and mapping, Vol. 1, Issue 6, pp. 409-13, (1992) (PubMed).

Target Details for HIST1H2AG

Target: HIST1H2AG (Histone Cluster 1, H2ag (HIST1H2AG))

Alternative Name: HIST1H2AG (HIST1H2AG Products)

Synonyms: H2A.1b antibody, H2A/p antibody, H2AFP antibody, H2AG antibody, pH2A/f antibody, histone cluster 1 H2A family member g antibody, histone H2A type 1 antibody, similar to Histone H2A type 1 antibody, HIST1H2AG antibody, LOC786163 antibody, LOC680322 antibody, LOC104968446 antibody

Background: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Molecular Weight: 14091

Gene ID: 8969

UniProt: P0C0S8