PACSIN3 antibody (N-Term)

Catalog No. ABIN2842165

Product Details anti-PACSIN3 Antibody

Target: PACSIN3 (Protein Kinase C and Casein Kinase Substrate in Neurons 3 (PACSIN3))

Binding Specificity: AA 1-30, N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PACSIN3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PACSIN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PACSIN3.

Clone: RB3577

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for PACSIN3

Target: PACSIN3 (Protein Kinase C and Casein Kinase Substrate in Neurons 3 (PACSIN3))

Alternative Name: PACSIN3 (PACSIN3 Products)

Synonyms: Pacsin1 antibody, wu:fa11d03 antibody, wu:fj67e09 antibody, wu:fq16a06 antibody, zgc:56324 antibody, MGC82145 antibody, PACSIN3 antibody, sdpiii antibody, SDPIII antibody, 4921507A02Rik antibody, 6330413E15Rik antibody, AW413130 antibody, SdpIII antibody, protein kinase C and casein kinase substrate in neurons 3 antibody, protein kinase C and casein kinase substrate in neurons 3 L homeolog antibody, pacsin3 antibody, PACSIN3 antibody, pacsin3.L antibody, Pacsin3 antibody

Background: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.

Molecular Weight: 48487

Gene ID: 29763

NCBI Accession: NP_001171903, NP_001171904, NP_057307

UniProt: Q9UKS6