MAPK8IP1 antibody (C-Term)

Catalog No. ABIN2842613

Product Details anti-MAPK8IP1 Antibody

Target: MAPK8IP1 (Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1))

Binding Specificity: AA 470-498, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAPK8IP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This JIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 470-498 amino acids from the C-terminal region of human JIP1.

Clone: RB23000

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for MAPK8IP1

Target: MAPK8IP1 (Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1))

Alternative Name: JIP1 (MAPK8IP1 Products)

Background: JIP1 is a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2.

Molecular Weight: 77524

Gene ID: 9479

NCBI Accession: NP_005447

UniProt: Q9UQF2