VCP antibody

Catalog No. ABIN284668

Product Details anti-VCP Antibody

Target: VCP (Valosin Containing Protein (VCP))

Reactivity: Xenopus laevis

Host: Mouse

Clonality: Monoclonal

Conjugate: This VCP antibody is un-conjugated

Application: Western Blotting (WB)

Purity: Culture supernatant

Immunogen: p97 ATPase antibody was raised in mouse using 15S Mg2+ ATPase complex purified from xenopus laevis ovary as the immunogen.

Clone: 58-13-3

Isotype: IgG1

Application Details

Application Notes: WB: 1:100-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Concentrated cell culture supernatant with 150 mM PBS, 0.1 % BSA, and 0.1 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

Storage: 4 °C

Storage Comment: Store at 4 °C

References for anti-VCP antibody (ABIN284668)

Ge, Tian, Liu, Wong, Gong, Wu, Cho, Lin, Kast, Lu, Wang: "p97 regulates GluA1 homomeric AMPA receptor formation and plasma membrane expression." in: Nature communications, Vol. 10, Issue 1, pp. 4089, (2019) (PubMed).

Zhou, Zhang, Anand, Stomberski, Qian, Hausladen, Wang, Rhee, Parikh, Karumanchi, Stamler: "Metabolic reprogramming by the S-nitroso-CoA reductase system protects against kidney injury." in: Nature, Vol. 565, Issue 7737, pp. 96-100, (2019) (PubMed).

Ye, Baek, Ye, Zhang: "Proteomic characterization of endogenous substrates of mammalian ubiquitin ligase Hrd1." in: Cell & bioscience, Vol. 8, pp. 46, (2018) (PubMed).

Fang, Hemion, Pinho Ferreira Bento, Bippes, Flammer, Neutzner: "Mitochondrial function in neuronal cells depends on p97/VCP/Cdc48-mediated quality control." in: Frontiers in cellular neuroscience, Vol. 9, pp. 16, (2015) (PubMed).

Baron, Pedrioli, Tyagi, Johnson, Wood, Fountaine, Wightman, Alexandru: "VAPB/ALS8 interacts with FFAT-like proteins including the p97 cofactor FAF1 and the ASNA1 ATPase." in: BMC biology, Vol. 12, pp. 39, (2014) (PubMed).

Jiang, Knox, Pathipati, Ferriero: "Developmental localization of NMDA receptors, Src and MAP kinases in mouse brain." in: Neuroscience letters, Vol. 503, Issue 3, pp. 215-9, (2011) (PubMed).

Ernst, Mueller, Ploegh, Schlieker: "The otubain YOD1 is a deubiquitinating enzyme that associates with p97 to facilitate protein dislocation from the ER." in: Molecular cell, Vol. 36, Issue 1, pp. 28-38, (2009) (PubMed).

Target Details for VCP

Target: VCP (Valosin Containing Protein (VCP))

Alternative Name: p97 ATPase (VCP Products)

Synonyms: ALS14 antibody, IBMPFD antibody, TERA antibody, p97 antibody, CDC48 antibody, wu:fd16d05 antibody, wu:fj63d11 antibody, p93 antibody, 3110001E05 antibody, p97/VCP antibody, 22.26 antibody, 7.12 antibody, Apple antibody, BcDNA.GM02885 antibody, BcDNA:GM02885 antibody, CG2331 antibody, DmTER94 antibody, Dmel\CG2331 antibody, I antibody, Ter94 antibody, Tera antibody, VCP antibody, VCP ATPase antibody, VCP/p97 antibody, Vcp antibody, anon-WO2004063362.65 antibody, anon-WO2004063362.67 antibody, cdc48 antibody, dTERA antibody, dVCP antibody, dmTERA antibody, dvcp antibody, l(2)03775 antibody, l(2)46CFf antibody, l(2)46CFs antibody, l(2)46Ch antibody, pTER94 antibody, ter94 antibody, vcp antibody, FANCG antibody, valosin containing protein antibody, valosin containing protein S homeolog antibody, valosin-containing protein antibody, CG2331 gene product from transcript CG2331-RA antibody, zgc:136908 antibody, transitional endoplasmic reticulum ATPase antibody, VCP antibody, vcp.S antibody, vcp antibody, Vcp antibody, Bm1_56585 antibody, LOC100136246 antibody, TER94 antibody, zgc:136908 antibody, LOC101109680 antibody

Pathways: ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Ubiquitin Proteasome Pathway