GP120 antibody

Catalog No. ABIN285167

Product Details anti-GP120 Antibody

Target: GP120 (HIV-1 gp120) (Human Immunodeficiency Virus 1 Surface Glycoprotein (HIV-1 gp120))

Reactivity: Human Immunodeficiency Virus (HIV)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GP120 antibody is un-conjugated

Application: ELISA, Immunoprecipitation (IP), Immunohistochemistry (IHC), Neutralization (Neut)

Purity: > 95 % pure

Immunogen: HIV1 gp120 antibody was raised in rabbit using HIV-1 gp120 as the immunogen.

Application Details

Application Notes: ELISA: 1:2,000, IHC: 1:200
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Supplied as a liquid in PBS.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: -80 °C

Storage Comment: Aliquot and store at -70 °C or lower.

References for anti-GP120 antibody (ABIN285167)

Kondo, Melikyan: "Intercellular adhesion molecule 1 promotes HIV-1 attachment but not fusion to target cells." in: PLoS ONE, Vol. 7, Issue 9, pp. e44827, (2013) (PubMed).

Miyauchi, Curran, Long, Kondo, Iwamoto, Engelman, Matsuda: "The membrane-spanning domain of gp41 plays a critical role in intracellular trafficking of the HIV envelope protein." in: Retrovirology, Vol. 7, pp. 95, (2010) (PubMed).

Target Details for GP120

Target: GP120 (HIV-1 gp120) (Human Immunodeficiency Virus 1 Surface Glycoprotein (HIV-1 gp120))

Alternative Name: HIV1 Gp120 (HIV-1 gp120 Products)

Target Type: Viral Protein

Background: Human immunodeficiency virus (HIV) is a lentivirus that causes acquired immunodeficiency syndrome (AIDS), a condition in humans in which the immune system begins to fail, leading to life-threatening opportunistic infections. Envelope glycoprotein GP120 (or gp120) is a glycoprotein exposed on the surface of the HIV envelope. The 120 in its name comes from its molecular weight of 120 kilodaltons. gp120 is essential for virus entry into cells as it plays a vital role in seeking out specific cell surface receptors for entry.