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Chitotriosidase 1 antibody

CHIT1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2854344
  • Target See all Chitotriosidase 1 (CHIT1) Antibodies
    Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))
    Reactivity
    • 31
    • 5
    • 2
    Human
    Host
    • 23
    • 9
    • 1
    Rabbit
    Clonality
    • 26
    • 7
    Polyclonal
    Conjugate
    • 22
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Chitotriosidase 1 antibody is un-conjugated
    Application
    • 20
    • 12
    • 9
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Cross-Reactivity
    Human
    Characteristics
    Rabbit polyclonal antibody to Chitotriosidase (chitinase 1 (chitotriosidase))
    Chitotriosidase antibody [N3C3]
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human CHIT1. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product CHIT1 Primary Antibody
  • Application Notes
    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: HeLa

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))
    Alternative Name
    chitinase 1 (CHIT1 Products)
    Synonyms
    CHI3 antibody, CHIT antibody, CHITD antibody, CHIT1 antibody, chio antibody, 2300002L19Rik antibody, chitinase 1 antibody, chitinase 1 (chitotriosidase) antibody, CHIT1 antibody, chit1 antibody, Chit1 antibody
    Background
    Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens.

    Cellular Localization: Secreted , Lysosome
    Molecular Weight
    52 kDa
    Gene ID
    1118
    UniProt
    Q13231
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