COL4a2 antibody

Catalog No. ABIN2854393

Product Details anti-COL4a2 Antibody

Target: COL4a2 (COL4A2) (Collagen, Type IV, alpha 2 (COL4A2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COL4a2 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human

Characteristics: Rabbit polyclonal antibody to Collagen IV alpha2 (collagen, type IV, alpha 2)
CO4A2 antibody [N2N3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human COL4A2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Validation: Orthogonal

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for COL4a2

Target: COL4a2 (COL4A2) (Collagen, Type IV, alpha 2 (COL4A2))

Alternative Name: collagen type IV alpha 2 chain (COL4A2 Products)

Background: This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. The C-terminal portion of the protein, known as canstatin, is an inhibitor of angiogenesis and tumor growth. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter.

Cellular Localization: Secreted , extracellular space , extracellular matrix , basement membrane

Molecular Weight: 168 kDa

Gene ID: 1284

UniProt: P08572