Arylsulfatase B antibody

Catalog No. ABIN2854408

Product Details anti-Arylsulfatase B Antibody

Target: Arylsulfatase B (ARSB)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Arylsulfatase B antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Rabbit polyclonal antibody to ARSB (arylsulfatase B)
ARSB antibody [N3C3]

Purification: Affinity purified by Protein A.

Immunogen: Recombinant protein encompassing a sequence within the center region of human ARSB. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: ARSB transfected 293T cell , HeLa , HepG2 , mouse placenta , rat testis

Validation: Overexpression

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 6.11 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for Arylsulfatase B

Target: Arylsulfatase B (ARSB)

Alternative Name: arylsulfatase B (ARSB Products)

Synonyms: ASB antibody, G4S antibody, MPS6 antibody, 1110007C02Rik antibody, AI480648 antibody, As-1 antibody, As-1r antibody, As-1s antibody, As-1t antibody, As1 antibody, As1-r antibody, As1-s antibody, As1-t antibody, Asr-1 antibody, Ast-1 antibody, ARSB antibody, arylsulfatase B antibody, arylsulfatase antibody, arylsulfatase b antibody, ARSB antibody, Arsb antibody, RB348 antibody, LOC5566067 antibody, CpipJ_CPIJ011047 antibody, VDBG_03275 antibody, arsb antibody, LOC5579667 antibody

Background: Arylsulfatase B encoded by this gene belongs to the sulfatase family. The arylsulfatase B homodimer hydrolyzes sulfate groups of N-Acetyl-D-galactosamine, chondriotin sulfate, and dermatan sulfate. The protein is targetted to the lysozyme. Mucopolysaccharidosis type VI is an autosomal recessive lysosomal storage disorder resulting from a deficiency of arylsulfatase B. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Cellular Localization: Lysosome

Molecular Weight: 60 kDa

Gene ID: 411

UniProt: P15848

Pathways: Glycosaminoglycan Metabolic Process