TBXAS1 antibody

Catalog No. ABIN2854414

Product Details anti-TBXAS1 Antibody

Target: TBXAS1 (thromboxane A Synthase 1 (Platelet) (TBXAS1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBXAS1 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Rat

Characteristics: Rabbit polyclonal antibody to TXA synthase (thromboxane A synthase 1 (platelet))
TXA synthase antibody [N3C3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human TXA synthase. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for TBXAS1

Target: TBXAS1 (thromboxane A Synthase 1 (Platelet) (TBXAS1))

Alternative Name: thromboxane A synthase 1 (TBXAS1 Products)

Synonyms: thas antibody, TBXAS1 antibody, wu:fk19d08 antibody, zgc:136708 antibody, BDPLT14 antibody, CYP5 antibody, CYP5A1 antibody, GHOSAL antibody, THAS antibody, TS antibody, TXAS antibody, TXS antibody, thromboxane-A synthase antibody, Thromboxane-A synthase antibody, thromboxane A synthase 1 antibody, thromboxane A synthase 1 (platelet) antibody, thromboxane A synthase 1, platelet antibody, PTRG_00454 antibody, PTRG_06796 antibody, thas antibody, TBXAS1 antibody, tbxas1 antibody, Tbxas1 antibody

Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Cellular Localization: Membrane, Multi-pass membrane protein

Molecular Weight: 61 kDa

Gene ID: 6916

UniProt: P24557