SHMT1 antibody

Catalog No. ABIN2854425

Product Details anti-SHMT1 Antibody

Target: SHMT1 (serine Hydroxymethyltransferase 1 (Soluble) (SHMT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SHMT1 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human

Characteristics: Rabbit Polyclonal antibody to SHMT1 (serine hydroxymethyltransferase 1 (soluble))
SHMT1 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human SHMT1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: U87-MG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for SHMT1

Target: SHMT1 (serine Hydroxymethyltransferase 1 (Soluble) (SHMT1))

Alternative Name: serine hydroxymethyltransferase 1 (SHMT1 Products)

Synonyms: Shmt antibody, mShmt antibody, LRRGT00032 antibody, shmt1 antibody, MGC53442 antibody, zgc:66171 antibody, zgc:77524 antibody, SHMT1 antibody, Shmt1 antibody, CSHMT antibody, SHMT antibody, AI324848 antibody, AI385541 antibody, C81125 antibody, mshmt antibody, mshmt1 antibody, mshmt2 antibody, MEL-32 antibody, SHMT2 antibody, F20D10.50 antibody, F20D10_50 antibody, SERINE HYDROXYMETHYLTRANSFERASE 1 antibody, SERINE TRANSHYDROXYMETHYLASE antibody, SERINE TRANSHYDROXYMETHYLTRANSFERASE antibody, STM antibody, serine transhydroxymethyltransferase 1 antibody, serine hydroxymethyltransferase 1 antibody, serine hydroxymethyltransferase 1 (soluble) L homeolog antibody, serine hydroxymethyltransferase 1 (soluble) antibody, microRNA 6778 antibody, serine transhydroxymethyltransferase 1 antibody, Shmt1 antibody, shmt1.L antibody, shmt1 antibody, MIR6778 antibody, SHMT1 antibody, SHM1 antibody

Background: This gene encodes the cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing of this gene results in 2 transcript variants encoding 2 different isoforms. Additional transcript variants have been described, but their biological validity has not been determined.

Cellular Localization: Cytoplasm

Molecular Weight: 53 kDa

Gene ID: 6470

UniProt: P34896