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PLCH1 antibody

PLCh1 Reactivity: Human WB, IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2854598
  • Target See all PLCH1 (PLCh1) Antibodies
    PLCH1 (PLCh1) (Phospholipase C eta 1 (PLCh1))
    Reactivity
    • 8
    • 2
    • 1
    Human
    Host
    • 9
    Rabbit
    Clonality
    • 9
    Polyclonal
    Conjugate
    • 9
    This PLCH1 antibody is un-conjugated
    Application
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Human
    Characteristics
    Rabbit polyclonal antibody to PLCH1 (phospholipase C, eta 1)
    PLCH1 antibody [N2C1], Internal
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human PLCH1. The exact sequence is proprietary.
    Isotype
    IgG
  • Application Notes
    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: A431 , HepG2

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.93 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Chomyk, Volsko, Tripathi, Deckard, Trapp, Fox, Dutta: "DNA methylation in demyelinated multiple sclerosis hippocampus." in: Scientific reports, Vol. 7, Issue 1, pp. 8696, (2019) (PubMed).

  • Target
    PLCH1 (PLCh1) (Phospholipase C eta 1 (PLCh1))
    Alternative Name
    phospholipase C eta 1 (PLCh1 Products)
    Synonyms
    PLCL3 antibody, BC042549 antibody, PLCeta1 antibody, Plcl3 antibody, RGD1561991 antibody, phospholipase C eta 1 antibody, phospholipase C, eta 1 antibody, PLCH1 antibody, Plch1 antibody
    Background
    PLCH1 is a member of the PLC-eta family of the phosphoinositide-specific phospholipase C (PLC) superfamily of enzymes that cleave phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) to generate second messengers inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) (Hwang et al., 2005 [PubMed 15702972]).[supplied by OMIM]

    Cellular Localization: Cytoplasm , Membrane
    Molecular Weight
    189 kDa
    Gene ID
    23007
    UniProt
    Q4KWH8
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