VEGFD antibody

Catalog No. ABIN2854869

Product Details anti-VEGFD Antibody

Target: VEGFD (Figf) (C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VEGFD antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Cow, Human

Characteristics: Rabbit Polyclonal antibody to VEGFD (c-fos induced growth factor (vascular endothelial growth factor D))
VEGFD antibody [N3C3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human VEGFD. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: 293T , Raji

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

References for anti-VEGFD antibody (ABIN2854869)

Huang, Sun, Ma, Gao, Li, Niu, Zhang, Chang: "Androgen receptor increases hematogenous metastasis yet decreases lymphatic metastasis of renal cell carcinoma." in: Nature communications, Vol. 8, Issue 1, pp. 918, (2018) (PubMed).

Target Details for VEGFD

Target: VEGFD (Figf) (C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf))

Alternative Name: vascular endothelial growth factor D (Figf Products)

Background: The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C.

Cellular Localization: Secreted

Molecular Weight: 40 kDa

Gene ID: 2277

UniProt: O43915

Pathways: RTK Signaling