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GALC antibody

GALC Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2854965
  • Target See all GALC Antibodies
    GALC (Galactosylceramidase (GALC))
    Reactivity
    • 29
    • 21
    • 18
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 32
    • 3
    Rabbit
    Clonality
    • 32
    • 3
    Polyclonal
    Conjugate
    • 17
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GALC antibody is un-conjugated
    Application
    • 33
    • 11
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human, Mouse
    Characteristics
    Rabbit polyclonal antibody to Galactosylceramidase (galactosylceramidase)
    Galactosylceramidase antibody [N3C3]
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human Galactosylceramidase. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product GALC Primary Antibody
  • Application Notes
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Validation:Orthogonal, Overexpression

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.46 mg/mL
    Buffer
    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    GALC (Galactosylceramidase (GALC))
    Alternative Name
    galactosylceramidase (GALC Products)
    Synonyms
    2310068B06Rik antibody, A930008M05Rik antibody, AW212969 antibody, AW413532 antibody, Gacy antibody, twi antibody, twitcher antibody, galc antibody, galcl antibody, zgc:92561 antibody, si:ch211-199l3.4 antibody, GALCERase antibody, wu:fi04e07 antibody, zgc:56444 antibody, galactosylceramidase antibody, galactosylceramidase a antibody, Galactosylceramidase antibody, galactosylceramidase L homeolog antibody, galactosylceramidase b antibody, GALC antibody, Galc antibody, galca antibody, galc antibody, Caci_7107 antibody, Bacsa_1415 antibody, Spico_0384 antibody, LOC100304802 antibody, galc.L antibody, galcb antibody
    Background
    This gene encodes a lysosomal protein which hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Mutations in this gene have been associated with Krabbe disease, also known as globoid cell leukodystrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

    Cellular Localization: Lysosome
    Molecular Weight
    77 kDa
    Gene ID
    2581
    UniProt
    P54803
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