Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

APOE antibody (N-Term)

APOE Reactivity: Human WB, IHC (p), ICC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2855049
  • Target See all APOE Antibodies
    APOE (Apolipoprotein E (APOE))
    Binding Specificity
    • 15
    • 15
    • 15
    • 5
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 101
    • 75
    • 56
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 102
    • 22
    • 13
    • 2
    Rabbit
    Clonality
    • 104
    • 34
    Polyclonal
    Conjugate
    • 59
    • 18
    • 12
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    This APOE antibody is un-conjugated
    Application
    • 110
    • 57
    • 39
    • 39
    • 30
    • 24
    • 20
    • 12
    • 9
    • 8
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Cross-Reactivity
    Human
    Characteristics
    Rabbit Polyclonal antibody to Apolipoprotein E (apolipoprotein E)
    Apolipoprotein E antibody
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the N-terminus region of human Apolipoprotein E. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product APOE Primary Antibody
  • Application Notes
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: A549 , human plasma

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Ellis, Naugler, Nauglers, Parini, Mörk, Jorns, Zemack, Sandblom, Björkhem, Ericzon, Wilson, Strom, Grompe: "Mice with chimeric livers are an improved model for human lipoprotein metabolism." in: PLoS ONE, Vol. 8, Issue 11, pp. e78550, (2014) (PubMed).

  • Target
    APOE (Apolipoprotein E (APOE))
    Alternative Name
    apolipoprotein E (APOE Products)
    Synonyms
    ad2 antibody, apoprotein antibody, im:7036787 antibody, wu:fb69a05 antibody, zgc:110064 antibody, apoe antibody, AI255918 antibody, AD2 antibody, LDLCQ5 antibody, LPG antibody, APOEA antibody, Apo-E antibody, apolipoprotein E antibody, apolipoprotein Ea antibody, apoe antibody, apoea antibody, Apoe antibody, APOE antibody
    Background
    Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.

    Cellular Localization: Secreted
    Molecular Weight
    36 kDa
    Gene ID
    348
    UniProt
    P02649
    Pathways
    Regulation of Cell Size, Lipid Metabolism
You are here:
Support