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IMPDH2 antibody

IMPDH2 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2855144
  • Target See all IMPDH2 Antibodies
    IMPDH2 (IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2))
    Reactivity
    • 51
    • 26
    • 24
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 45
    • 5
    • 1
    Rabbit
    Clonality
    • 40
    • 11
    Polyclonal
    Conjugate
    • 30
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This IMPDH2 antibody is un-conjugated
    Application
    • 31
    • 15
    • 13
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Rabbit Polyclonal antibody to IMP dehydrogenase 2 (IMP (inosine monophosphate) dehydrogenase 2)
    IMPDH2 antibody [N2C1], Internal
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human IMPDH2. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product IMPDH2 Primary Antibody
  • Application Notes
    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: Mouse brain , H1299 , HepG2

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.17 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    IMPDH2 (IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2))
    Alternative Name
    inosine monophosphate dehydrogenase 2 (IMPDH2 Products)
    Synonyms
    imp2 antibody, impd2 antibody, impdh-ii antibody, impdh2 antibody, IMPD2 antibody, IMPDH-II antibody, IMPD 2 antibody, IMPDH 2 antibody, cb635 antibody, wu:fb64g02 antibody, wu:fc43f09 antibody, IMPD antibody, inosine monophosphate dehydrogenase 2 antibody, IMP (inosine 5'-monophosphate) dehydrogenase 2 antibody, inosine 5'-phosphate dehydrogenase 2 antibody, IMPDH2 antibody, impdh2.S antibody, impdh2 antibody, Impdh2 antibody
    Background
    This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.

    Molecular Weight
    56 kDa
    Gene ID
    3615
    UniProt
    P12268
    Pathways
    Ribonucleoside Biosynthetic Process, SARS-CoV-2 Protein Interactome
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