HSV1/2 antibody

Catalog No. ABIN285517

Product Details anti-HSV1/2 Antibody

Target: HSV1/2 (Herpes Simplex Virus Type 1/2 (HSV1/2))

Reactivity: Herpes Simplex Virus (HSV)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSV1/2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: This antibody conjugate fluoresces and agglutinates fresh mouse RBS but doesnot fluoresce or agglutinate fixed mouse RBC's

Cross-Reactivity (Details): This lot of antibody crossreacts to HSV 1&2. Specific for the ICP's and late structural (virion) antigens. No reactivity was observed to HEp-2 cells.

Purity: > 95 % pure

Immunogen: HSV1/HSV2 antibody was raised in rabbit using Strain F as the immunogen.

Application Details

Application Notes: Optimal conditions should be determined byt he investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: PBS, pH 7.2, with 0.1 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

References for anti-HSV1/2 antibody (ABIN285517)

Yang, Wang, Ketkar, Ma, Yang, Cui, Geng, Mordue, Fujimoto, Cheng, You, Lin, Fikrig, Wang: "UBXN3B positively regulates STING-mediated antiviral immune responses." in: Nature communications, Vol. 9, Issue 1, pp. 2329, (2018) (PubMed).

Roller, Dollery, Doyle, Nicola: "Structure-function analysis of herpes simplex virus glycoprotein B with fusion-from-without activity." in: Virology, Vol. 382, Issue 2, pp. 207-16, (2008) (PubMed).

Delboy, Patterson, Hollander, Nicola: "Nectin-2-mediated entry of a syncytial strain of herpes simplex virus via pH-independent fusion with the plasma membrane of Chinese hamster ovary cells." in: Virology journal, Vol. 3, pp. 105, (2007) (PubMed).

Target Details for HSV1/2

Target: HSV1/2 (Herpes Simplex Virus Type 1/2 (HSV1/2))

Alternative Name: HSV1, HSV2 (HSV1/2 Products)

Target Type: Virus

Background: Herpes simplex virus 1 and 2 (HSV-1 and HSV-2), also known as Human herpes virus 1 and 2 (HHV-1 and -2), are two members of the herpes virus family, Herpesviridae, that infect humans. Both HSV-1 (which produces cold sores) and HSV-2 (which produces genital herpes) are ubiquitous and contagious. They can be spread when an infected person is producing and shedding the virus.