MRPL23 antibody

Catalog No. ABIN2855288

Product Details anti-MRPL23 Antibody

Target: MRPL23 (Mitochondrial Ribosomal Protein L23 (MRPL23))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL23 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Rat

Characteristics: Rabbit polyclonal antibody to MRPL23 (mitochondrial ribosomal protein L23)
MRPL23 antibody [N1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human MRPL23. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.61 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for MRPL23

Target: MRPL23 (Mitochondrial Ribosomal Protein L23 (MRPL23))

Alternative Name: mitochondrial ribosomal protein L23 (MRPL23 Products)

Synonyms: BcDNA:RE49852 antibody, CG1320 antibody, Dmel\\CG1320 antibody, L23 antibody, L23MRP antibody, RPL23 antibody, RPL23L antibody, L23mrp antibody, Rpl23 antibody, Rpl23l antibody, Rpl23-rs antibody, rL23MRP antibody, zgc:86630 antibody, mitochondrial ribosomal protein L23 antibody, mRpL23 antibody, MRPL23 antibody, Mrpl23 antibody, mrpl23 antibody

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. The gene is biallelically expressed, despite its location within a region of imprinted genes on chromosome 11.

Cellular Localization: Mitochondrion

Molecular Weight: 18 kDa

Gene ID: 6150

UniProt: Q16540