IGFALS antibody (C-Term)

Catalog No. ABIN2855350

Product Details anti-IGFALS Antibody

Target: IGFALS (Insulin-Like Growth Factor Binding Protein, Acid Labile Subunit (IGFALS))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGFALS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human

Characteristics: Rabbit Polyclonal antibody to ALS (insulin-like growth factor binding protein, acid labile subunit)
ALS antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human ALS. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: THP-1

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for IGFALS

Target: IGFALS (Insulin-Like Growth Factor Binding Protein, Acid Labile Subunit (IGFALS))

Alternative Name: insulin like growth factor binding protein acid labile subunit (IGFALS Products)

Synonyms: ALS antibody, Albs antibody, mKIAA4111 antibody, Als antibody, insulin like growth factor binding protein acid labile subunit antibody, insulin like growth factor binding protein acid labile subunit L homeolog antibody, insulin-like growth factor binding protein, acid labile subunit antibody, IGFALS antibody, igfals.L antibody, Igfals antibody

Background: The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene.

Cellular Localization: Secreted , extracellular space

Molecular Weight: 66 kDa

Gene ID: 3483

UniProt: P35858