BMPR1B antibody
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- Target See all BMPR1B Antibodies
- BMPR1B (Bone Morphogenetic Protein Receptor, Type IB (BMPR1B))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This BMPR1B antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Cross-Reactivity
- Cow, Human, Mouse, Rat
- Characteristics
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Rabbit polyclonal antibody to BMPR1B (bone morphogenetic protein receptor, type IB)
BMPR1B antibody [N3C3] - Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human BMPR1B. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product BMPR1B Primary Antibody
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- Application Notes
- WB: 1:500-1:10000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Comment
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Positive Control: 293T , A431 , HeLa , HepG2 , human BMPR1B-transfected 293T cells , Neuro2A , C8D30 , NIH-3T3 , Rat2
Validation: Overexpression
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1 mg/mL
- Buffer
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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Estrogen mediated epithelial proliferation in the uterus is directed by stromal Fgf10 and Bmp8a." in: Molecular and cellular endocrinology, Vol. 400, pp. 48-60, (2015) (PubMed).
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Estrogen mediated epithelial proliferation in the uterus is directed by stromal Fgf10 and Bmp8a." in: Molecular and cellular endocrinology, Vol. 400, pp. 48-60, (2015) (PubMed).
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- Target
- BMPR1B (Bone Morphogenetic Protein Receptor, Type IB (BMPR1B))
- Alternative Name
- bone morphogenetic protein receptor type 1B (BMPR1B Products)
- Synonyms
- ALK6 antibody, BMPR-IB antibody, FecB antibody, alk-6 antibody, alk6 antibody, cdw293 antibody, alk6b antibody, zgc:172219 antibody, BMPR1B antibody, AI385617 antibody, ALK-6 antibody, AV355320 antibody, Acvrlk6 antibody, Alk6 antibody, BMPR-1B antibody, CFK-43a antibody, SKR6 antibody, BR1b antibody, alk6tr antibody, bmpr1b antibody, zALK-6 antibody, zgc:92220 antibody, CDw293 antibody, BMP15 antibody, BMPRIB antibody, RPK-1 antibody, bone morphogenetic protein receptor type 1B antibody, bone morphogenetic protein receptor, type IBb antibody, bone morphogenetic protein receptor, type 1B antibody, bone morphogenetic protein receptor, type IBa antibody, BMPR1B antibody, bmpr1b antibody, bmpr1bb antibody, Bmpr1b antibody, bmpr1ba antibody
- Background
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This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension.
Cellular Localization: Membrane - Molecular Weight
- 57 kDa
- Gene ID
- 658
- UniProt
- O00238
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