SERPINH1 antibody (Internal Region)

Catalog No. ABIN2855536

Product Details anti-SERPINH1 Antibody

Target: SERPINH1 (Serpin Family H Member 1 (SERPINH1))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SERPINH1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Chimpanzee, Rhesus Monkey

Cross-Reactivity (Details): Rhesus Monkey (100 %), Chimpanzee (100 %)

Characteristics: Rabbit Polyclonal antibody to HSP47 (serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1))
HSP47 antibody [N2C2], Internal

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human HSP47. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Comment:

Positive Control: NIH-3T3 , A431 , HeLa , HepG2 , U87-MG , SK-N-SH , IMR32 , SK-N-AS

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.37 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for SERPINH1

Target: SERPINH1 (Serpin Family H Member 1 (SERPINH1))

Alternative Name: HSP47 (SERPINH1 Products)

Synonyms: AsTP3 antibody, CBP1 antibody, CBP2 antibody, HSP47 antibody, OI10 antibody, PPROM antibody, RA-A47 antibody, SERPINH2 antibody, gp46 antibody, SERPINH1 antibody, DKFZp468B197 antibody, cb216 antibody, hsp antibody, hsp47 antibody, id:ibd5060 antibody, wu:fc56b02 antibody, BERF-1 antibody, Cbp1 antibody, Cbp2 antibody, Hsp47 antibody, J6 antibody, Serpinh2 antibody, colligin antibody, astp3 antibody, cbp1 antibody, cbp2 antibody, pig14 antibody, pprom antibody, ra-a47 antibody, serpinh2 antibody, serpin family H member 1 antibody, serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b antibody, serpin H1 antibody, selenoprotein K antibody, serine (or cysteine) peptidase inhibitor, clade H, member 1 antibody, serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) L homeolog antibody, SERPINH1 antibody, serpinh1b antibody, LOC100009353 antibody, Selenok antibody, Serpinh1 antibody, serpinh1.L antibody

Target Type: Viral Protein

Background: This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. Its expression is induced by heat shock. The protein localizes to the endoplasmic reticulum lumen and binds collagen, thus it is thought to be a molecular chaperone involved in the maturation of collagen molecules. Autoantibodies to this protein have been found in patients with rheumatoid arthritis.

Cellular Localization: Endoplasmic reticulum lumen

Molecular Weight: 46 kDa

Gene ID: 871