MANBA antibody

Catalog No. ABIN2855559

Product Details anti-MANBA Antibody

Target: MANBA (Mannosidase, beta A, Lysosomal (MANBA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MANBA antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human

Characteristics: Rabbit polyclonal antibody to MANBA (mannosidase, beta A, lysosomal)
MANBA antibody [N3C2], Internal

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human MANBA. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HepG2

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for MANBA

Target: MANBA (Mannosidase, beta A, Lysosomal (MANBA))

Alternative Name: mannosidase beta (MANBA Products)

Synonyms: zgc:55493 antibody, zgc:76896 antibody, MGC82825 antibody, SC2H4.14 antibody, MANB1 antibody, 2410030O07Rik antibody, B930014J03Rik antibody, Bmn antibody, mannosidase, beta A, lysosomal antibody, mannosidase beta antibody, mannosidase, beta A, lysosomal L homeolog antibody, Probable beta-mannosidase antibody, beta-mannosidase antibody, Beta-mannosidase antibody, manba antibody, MANBA antibody, manba.L antibody, C33G3.4 antibody, SCO6232 antibody, bmnA antibody, THAPSDRAFT_262343 antibody, Jden_1756 antibody, PAAG_08337 antibody, Ndas_4827 antibody, Spirs_1196 antibody, VDBG_07992 antibody, RBRH_03524 antibody, Manba antibody

Background: This gene encodes a member of the glycosyl hydrolase 2 family. The encoded protein localizes to the lysosome where it is the final exoglycosidase in the pathway for N-linked glycoprotein oligosaccharide catabolism. Mutations in this gene are associated with beta-mannosidosis, a lysosomal storage disease that has a wide spectrum of neurological involvement.

Cellular Localization: Lysosome

Molecular Weight: 101 kDa

Gene ID: 4126

UniProt: O00462