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RFC3 antibody

RFC3 Reactivity: Human WB, IHC (p), IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2855682
  • Target See all RFC3 Antibodies
    RFC3 (Replication Factor C (Activator 1) 3, 38kDa (RFC3))
    Reactivity
    • 35
    • 18
    • 16
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 29
    • 6
    Rabbit
    Clonality
    • 32
    • 3
    Polyclonal
    Conjugate
    • 28
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RFC3 antibody is un-conjugated
    Application
    • 26
    • 9
    • 9
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Cross-Reactivity
    Human
    Characteristics
    Rabbit Polyclonal antibody to RFC3 (replication factor C (activator 1) 3, 38 kDa)
    RFC3 antibody
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human RFC3. The exact sequence is proprietary.
    Isotype
    IgG
  • Application Notes
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: HeLa

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.43 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    RFC3 (Replication Factor C (Activator 1) 3, 38kDa (RFC3))
    Alternative Name
    replication factor C subunit 3 (RFC3 Products)
    Synonyms
    CG5313 antibody, DRFC antibody, DmRFC3 antibody, Dmel\\CG5313 antibody, Rfc3 antibody, 21.m02902 antibody, 2810416I22Rik antibody, 38kDa antibody, AU022547 antibody, Recc3 antibody, cb275 antibody, RFC38 antibody, Replication factor C subunit 3 antibody, replication factor C3 antibody, replication factor C subunit 3 antibody, replication factor C 38 kDa subunit antibody, DNA replication factor C complex subunit Rfc3 antibody, replication factor C3, putative antibody, replication factor C (activator 1) 3 antibody, replication factor C subunit 3 L homeolog antibody, RfC3 antibody, PF14_0601 antibody, Chro.30359 antibody, PB000006.01.0 antibody, PC000345.04.0 antibody, TP04_0380 antibody, Tb09.211.3310 antibody, PY04255 antibody, PVX_117300 antibody, BBOV_IV003080 antibody, SJAG_02182 antibody, PKH_124240 antibody, rfc3 antibody, Rfc3 antibody, RFC3 antibody, rfc3.L antibody
    Background
    The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kDa. This gene encodes the 38 kDa subunit. This subunit is essential for the interaction between the 140 kDa subunit and the core complex that consists of the 36, 37, and 40 kDa subunits. Alternatively spliced transcript variants encoding distinct isoforms have been described.

    Cellular Localization: Nucleus
    Molecular Weight
    41 kDa
    Gene ID
    5983
    UniProt
    P40938
    Pathways
    Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA
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