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IDH3A antibody

IDH3A Reactivity: Human WB, IF, IHC (p), ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2855763
  • Target See all IDH3A Antibodies
    IDH3A (Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A))
    Reactivity
    • 43
    • 31
    • 17
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 39
    • 3
    • 1
    Rabbit
    Clonality
    • 41
    • 2
    Polyclonal
    Conjugate
    • 18
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This IDH3A antibody is un-conjugated
    Application
    • 32
    • 13
    • 13
    • 11
    • 10
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Cross-Reactivity
    Human, Mouse, Rat, Zebrafish (Danio rerio)
    Characteristics
    Rabbit Polyclonal antibody to IDH3A (isocitrate dehydrogenase 3 (NAD+) alpha)
    IDH3A antibody
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human IDH3A. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product IDH3A Primary Antibody
  • Application Notes
    WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: Mouse brain , rat brain

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.84 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    IDH3A (Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A))
    Alternative Name
    isocitrate dehydrogenase 3 (NAD(+)) alpha (IDH3A Products)
    Synonyms
    idh3a antibody, MGC76128 antibody, IDH3A antibody, zgc:56380 antibody, zgc:85631 antibody, BG1 antibody, 1110003P10Rik antibody, 1500012E04Rik antibody, AA407078 antibody, AI316514 antibody, isocitrate dehydrogenase 3 (NAD+) alpha antibody, isocitrate dehydrogenase 3 (NAD(+)) alpha antibody, isocitrate dehydrogenase 3 (NAD+) alpha S homeolog antibody, idh3a antibody, IDH3A antibody, idh3a.S antibody, Idh3a antibody
    Background
    Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.

    Cellular Localization: Mitochondrion
    Molecular Weight
    40 kDa
    Gene ID
    3419
    UniProt
    P50213
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