CLIC3 antibody

Catalog No. ABIN2855820

Product Details anti-CLIC3 Antibody

Target: CLIC3 (Chloride Intracellular Channel 3 (CLIC3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLIC3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse

Characteristics: Rabbit polyclonal antibody to CLIC3 (chloride intracellular channel 3)
CLIC3 antibody [N1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human CLIC3. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HeLaS3

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.74 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for CLIC3

Target: CLIC3 (Chloride Intracellular Channel 3 (CLIC3))

Alternative Name: chloride intracellular channel 3 (CLIC3 Products)

Synonyms: MGC84171 antibody, CLIC3 antibody, 2300003G24Rik antibody, chloride intracellular channel 3 antibody, chloride intracellular channel 3 L homeolog antibody, chloride intracellular channel 3-like antibody, Clic3 antibody, clic3.L antibody, CLIC3 antibody, CLIC3L antibody

Background: Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH , and regulation of cell volume. Chloride intracellular channel 3 is a member of the p64 family and is predominantly localized in the nucleus and stimulates chloride ion channel activity. In addition, this protein may participate in cellular growth control, based on its association with ERK7, a member of the MAP kinase family.

Cellular Localization: Nucleus , Membrane , Cytoplasm

Molecular Weight: 27 kDa

Gene ID: 9022

UniProt: O95833