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CASQ2 antibody

CASQ2 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2856218
  • Target See all CASQ2 Antibodies
    CASQ2 (Calsequestrin 2 (CASQ2))
    Reactivity
    • 31
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 27
    • 5
    Rabbit
    Clonality
    • 28
    • 4
    Polyclonal
    Conjugate
    • 17
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CASQ2 antibody is un-conjugated
    Application
    • 21
    • 16
    • 6
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human, Mouse
    Characteristics
    Rabbit polyclonal antibody to Calsequestrin-2 (calsequestrin 2 (cardiac muscle))
    Calsequestrin-2 antibody
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human Calsequestrin 2. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product CASQ2 Primary Antibody
  • Application Notes
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: HCT116

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.68 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    CASQ2 (Calsequestrin 2 (CASQ2))
    Alternative Name
    calsequestrin 2 (CASQ2 Products)
    Synonyms
    CASQ2 antibody, DKFZp468D075 antibody, AA033488 antibody, AW146219 antibody, ESTM52 antibody, cCSQ antibody, PDIB2 antibody, cardCSQ antibody, CASQ1 antibody, CAL antibody, calsequestrin 2 antibody, CASQ2 antibody, Casq2 antibody
    Background
    The protein encoded by this gene specifies the cardiac muscle family member of the calsequestrin family. Calsequestrin is localized to the sarcoplasmic reticulum in cardiac and slow skeletal muscle cells. The protein is a calcium binding protein that stores calcium for muscle function. Mutations in this gene cause stress-induced polymorphic ventricular tachycardia, also referred to as catecholaminergic polymorphic ventricular tachycardia 2 (CPVT2), a disease characterized by bidirectional ventricular tachycardia that may lead to cardiac arrest.

    Cellular Localization: Sarcoplasmic reticulum lumen
    Molecular Weight
    46 kDa
    Gene ID
    845
    UniProt
    O14958
    Pathways
    Negative Regulation of Transporter Activity
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