PHEX antibody

Catalog No. ABIN2856237

Product Details anti-PHEX Antibody

Target: PHEX (Phosphate Regulating Endopeptidase Homolog, X-Linked (PHEX))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHEX antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human

Characteristics: Rabbit polyclonal antibody to PHEX (phosphate regulating endopeptidase homolog, X-linked)
PHEX antibody [N1N3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human PHEX. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Molt-4

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.99 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for PHEX

Target: PHEX (Phosphate Regulating Endopeptidase Homolog, X-Linked (PHEX))

Alternative Name: phosphate regulating endopeptidase homolog X-linked (PHEX Products)

Synonyms: HPDR antibody, HPDR1 antibody, HYP antibody, HYP1 antibody, LXHR antibody, PEX antibody, XLH antibody, Gy antibody, Hyp antibody, phosphate regulating endopeptidase homolog X-linked antibody, phosphate regulating endopeptidase homolog, X-linked antibody, PHEX antibody, Phex antibody

Background: The protein encoded by this gene is a transmembrane endopeptidase that belongs to the type II integral membrane zinc-dependent endopeptidase family. The protein is thought to be involved in bone and dentin mineralization and renal phosphate reabsorption. Mutations in this gene cause X-linked hypophosphatemic rickets.

Cellular Localization: Membrane, Single-pass type II membrane protein

Molecular Weight: 86 kDa

Gene ID: 5251

UniProt: P78562