TMEM67 antibody (Center)

Catalog No. ABIN2856740

Product Details anti-TMEM67 Antibody

Target: TMEM67 (Transmembrane Protein 67 (TMEM67))

Binding Specificity: Center

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM67 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human

Characteristics: Rabbit polyclonal antibody to Meckelin (transmembrane protein 67)
meckelin isoform 1 antibody [N2C1], Internal

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human meckelin isoform 1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: H1299

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for TMEM67

Target: TMEM67 (Transmembrane Protein 67 (TMEM67))

Alternative Name: transmembrane protein 67 (TMEM67 Products)

Synonyms: JBTS6 antibody, MECKELIN antibody, MKS3 antibody, NPHP11 antibody, TNEM67 antibody, 5330408M12Rik antibody, B230117O07 antibody, b2b1163.1Clo antibody, b2b1291.1Clo antibody, Wpk antibody, transmembrane protein 67 antibody, TMEM67 antibody, tmem67 antibody, Tmem67 antibody

Background: The protein encoded by this gene localizes to the primary cilium and to the plasma membrane. The gene functions in centriole migration to the apical membrane and formation of the primary cilium. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Meckel syndrome type 3 (MKS3) and Joubert syndrome type 6 (JBTS6).

Cellular Localization: Cell membrane, Multi-pass membrane protein

Molecular Weight: 112 kDa

Gene ID: 91147

UniProt: Q5HYA8