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Fatty Acid Synthase antibody (N-Term)

KO Validated FASN Reactivity: Human WB, IP, IF, ICC, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2856754
  • Target See all Fatty Acid Synthase (FASN) Antibodies
    Fatty Acid Synthase (FASN)
    Binding Specificity
    • 15
    • 6
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 73
    • 40
    • 34
    • 16
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 58
    • 19
    • 2
    Rabbit
    Clonality
    • 53
    • 26
    Polyclonal
    Conjugate
    • 54
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Fatty Acid Synthase antibody is un-conjugated
    Application
    • 63
    • 24
    • 21
    • 20
    • 20
    • 16
    • 14
    • 14
    • 13
    • 5
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human, Mouse
    Characteristics
    Rabbit Polyclonal antibody to Fatty Acid Synthase (fatty acid synthase)
    Fatty Acid Synthase antibody [N1N2], N-term
    Purification
    Purified by antigen-affinity chromatography.
    Grade
    KO Validated
    Immunogen
    Recombinant protein encompassing a sequence within the N-terminus region of human Fatty Acid Synthase. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product FASN Primary Antibody
  • Application Notes
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: Molt-4 , 293T , A431 , HeLa , HepG2

    Validation: KO/KD, Orthogonal

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    Fatty Acid Synthase (FASN)
    Alternative Name
    fatty acid synthase (FASN Products)
    Synonyms
    FAS antibody, OA-519 antibody, SDR27X1 antibody, FASN antibody, fj34h12 antibody, wu:fj34h12 antibody, Cgl0836 antibody, A630082H08Rik antibody, BcDNA:GH07626 antibody, BcDNA:gh07626 antibody, DM_7295848 antibody, Dmel\\CG3523 antibody, Fatty acid synthase antibody, anon-EST:Posey235 antibody, anon-EST:Posey43 antibody, anon-WO0138581.1 antibody, dFAS antibody, fas antibody, fatty acid synthase antibody, fatty acid synthase Fas antibody, type I polyketide synthase antibody, Fatty acid synthase Fas antibody, Fatty Acid SyNthase antibody, fatty-acid synthase antibody, fatty-acid synthase II antibody, fatty-acid synthase fas antibody, Fatty acid synthase 1 antibody, FASN antibody, fas antibody, Fasn antibody, BAD_RS01360 antibody, fasn antibody, fasn-1 antibody, NCgl0802 antibody, fasB antibody, MT2600 antibody, TBMG_01448 antibody, FASN1 antibody
    Background
    The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.

    Cellular Localization: Cytoplasm , Melanosome
    Molecular Weight
    273 kDa
    Gene ID
    2194
    UniProt
    P49327
    Pathways
    AMPK Signaling
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