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CAMK2D antibody

KO Validated CAMK2D Reactivity: Human WB, IF, IHC (p), ICC, IP Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2856806
  • Target See all CAMK2D Antibodies
    CAMK2D (Calcium/calmodulin-Dependent Protein Kinase II delta (CAMK2D))
    Reactivity
    • 67
    • 44
    • 38
    • 10
    • 9
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 78
    • 4
    Rabbit
    Clonality
    • 69
    • 13
    Polyclonal
    Conjugate
    • 34
    • 7
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    This CAMK2D antibody is un-conjugated
    Application
    • 67
    • 35
    • 32
    • 13
    • 12
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunoprecipitation (IP)
    Specificity
    Cross-reactivity may occur with other CaM kinase II subunits.
    Cross-Reactivity
    Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
    Characteristics
    Rabbit Polyclonal antibody to CaMKII delta (calcium/calmodulin-dependent protein kinase II delta)
    CaMKII delta antibody
    Purification
    Purified by antigen-affinity chromatography.
    Grade
    KO Validated
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human CaMKII delta. The exact sequence is proprietary.
    Isotype
    IgG
  • Application Notes
    WB: 1:500-1:50000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: A549 , H1299 , HCT116 , 293T , A431 , HeLa , HepG2 , mouse brain , rat brain

    Validation: KO/KD, Orthogonal

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.62 mg/mL
    Buffer
    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Liu, Zhong, Zhou, Yang, Tan, Li, Gao, Sun, Li, Jin, Cao, Yuan, Liu, Liang, Li, Du, Zhao, Xue, Zhao, Song, Ling, Li: "Alteration of calcium signalling in cardiomyocyte induced by simulated microgravity and hypergravity." in: Cell proliferation, Vol. 53, Issue 3, pp. e12783, (2020) (PubMed).

    Li, Liu, Li, Zheng, Xu, Liu, Sun, Li, Ji, Liu, Zhang, Zhao, Du, Liu, Zhong, Sun, Wang, Song, Zhang, Qin, Ling, Wang, Li: "TMCO1-mediated Ca2+ leak underlies osteoblast functions via CaMKII signaling." in: Nature communications, Vol. 10, Issue 1, pp. 1589, (2019) (PubMed).

    Xu, Wang, Zhang, Gong, Gutierrez Cortes, Zhu, Yoon, Tian, Wang: "CaMKII induces permeability transition through Drp1 phosphorylation during chronic β-AR stimulation." in: Nature communications, Vol. 7, pp. 13189, (2016) (PubMed).

  • Target
    CAMK2D (Calcium/calmodulin-Dependent Protein Kinase II delta (CAMK2D))
    Alternative Name
    calcium/calmodulin dependent protein kinase II delta (CAMK2D Products)
    Synonyms
    CAMKD antibody, CAMK1 antibody, Camk2 antibody, Camki antibody, RATCAMKI antibody, camk2 antibody, camkd antibody, camkII antibody, 2810011D23Rik antibody, 8030469K03Rik antibody, [d]-CaMKII antibody, mKIAA4163 antibody, calcium/calmodulin dependent protein kinase II delta antibody, calcium/calmodulin-dependent protein kinase II delta antibody, calcium/calmodulin dependent protein kinase (CaM kinase) II delta S homeolog antibody, calcium/calmodulin dependent protein kinase (CaM kinase) II delta antibody, calcium/calmodulin-dependent protein kinase II, delta antibody, CAMK2D antibody, Camk2d antibody, camk2d.S antibody, camk2d antibody
    Background
    The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a delta chain. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Distinct isoforms of this chain have different expression patterns.

    Molecular Weight
    56 kDa
    Gene ID
    817
    UniProt
    Q13557
    Pathways
    WNT Signaling, Interferon-gamma Pathway, Myometrial Relaxation and Contraction, Smooth Muscle Cell Migration
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