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CXCR4 antibody (Extracellular Domain, N-Term)
CXCR4
Reactivity: Mouse
WB, ELISA, IHC
Host: Goat
Polyclonal
unconjugated
Product Details anti-CXCR4 Antibody
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Target
See all CXCR4 Antibodies
CXCR4
(Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
Binding Specificity
All epitopes for CXCR4 antibodies
Extracellular Domain, N-Term
Reactivity
All reactivities for CXCR4 antibodies
Mouse
Host
All hosts for CXCR4 antibodies
Goat
Clonality
All clonalities for CXCR4 antibodies
Polyclonal
Conjugate
All conjugates for CXCR4 antibodies
This CXCR4 antibody is un-conjugated
Application
All applications for CXCR4 antibodies
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
Cross-Reactivity
Xenopus laevis
Immunogen
CXCR4 antibody was raised in goat using YSEEVGSGDYDSNKEPCFRDENVHFNR corresponding to the N-terminal extracellular domain of mouse CXCR4 receptor. as the immunogen.
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Alternatives
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Application Details
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Application Notes
ELISA: 1:25,000, IHC: 1:150, WB: 1:500 Optimal conditions should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
Lot specific
Buffer
10 mM KHPO4, 140 M NaCl with 1 mg/mL BSA and 0.1 % NaN3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handling Advice
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Storage
-20 °C/-80 °C
Storage Comment
Aliquot and store at -20 °C for short term storage, -70 °C for long-term storage.
Target Details for CXCR4
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Target
CXCR4
(Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
Alternative Name
CXCR4 (CXCR4 Products )
Synonyms
CD184 antibody, D2S201E antibody, FB22 antibody, HM89 antibody, HSY3RR antibody, LAP3 antibody, LCR1 antibody, LESTR antibody, NPY3R antibody, NPYR antibody, NPYRL antibody, NPYY3R antibody, WHIM antibody, Cmkar4 antibody, PB-CKR antibody, PBSF/SDF-1 antibody, Sdf1r antibody, CXC-R4-B antibody, CXCR-4-B antibody, cd184 antibody, cxcr4 antibody, fb22 antibody, hm89 antibody, hsy3rr antibody, lap3 antibody, lcr1 antibody, lestr antibody, npy3r antibody, npyr antibody, npyrl antibody, npyy3r antibody, xcxcr4 antibody, CXC-R4 antibody, CXCR-4 antibody, d2s201e antibody, whim antibody, CXC-R4-A antibody, CXCR-4-A antibody, xCXCR4 antibody, CXCR4 antibody, cb403 antibody, zgc:109863 antibody, cb824 antibody, C-X-C motif chemokine receptor 4 antibody, chemokine (C-X-C motif) receptor 4 antibody, C-X-C motif chemokine receptor 4 S homeolog antibody, C-X-C chemokine receptor type 4 antibody, C-X-C motif chemokine receptor 4 L homeolog antibody, chemokine (C-X-C motif), receptor 4b antibody, chemokine (C-X-C motif) receptor 4a antibody, CXCR4 antibody, Cxcr4 antibody, cxcr4.S antibody, cxcr4 antibody, LOC100049444 antibody, cxcr4.L antibody, cxcr4b antibody, cxcr4a antibody
Background
Chemokine receptors are G protein-coupled receptors (GPCRs) and play a key role in inflammation and are characterized by similar sequences with a 4 cysteine motif. CXCR-4 is an alpha-chemokine receptor specific for stromal-derived-factor-1 (SDF-1 also called CXCL12), a molecule endowed with potent chemotactic activity for lymphocytes.
Pathways
Regulation of Cell Size , CXCR4-mediated Signaling Events
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